The first two games placed little focus on visuals, and New Blood follows suit. If you're the type who can't stand the sight of blood or any type of medical procedure, don't let the fact that this is a surgery-based simulator put you off. Most of the emphasis seems to be on making the game easy to play. The game doesn't go for realism; so the vital organ you're working on only vaguely looks like the body part it is supposed to represent. There's blood, but it is really just a cloud of red splatter.
Anime-styled characters pop up between surgeries to push the story along. As with previous games, they aren't animated, but they do change expressions to go along with the text. The accompanying voicework is good, though it is wasted on really bad, over-the-top dialogue. The funny thing is, it is so well crafted and worded, that I could never figure out if it was meant to be as bad as it is, or if it just dumb luck. Although bad, it shouldn't put off many players, especially those who watch anime since they're already accustomed to characters summoning the stars, ancestors and a long-dead pet gerbil, Patches, before performing any action.